EFFECTS OF CHRONIC SLEEP DEPRIVATION ON THE EXTRACELLULAR SIGNAL-REGULATED KINASE PATHWAY IN THE TEMPOROMANDIBULAR JOINT OF RATS.

Effects of chronic sleep deprivation on the extracellular signal-regulated kinase pathway in the temporomandibular joint of rats.

OBJECTIVES: To examine the possible involvement and Twin Coverlet Set regulatory mechanisms of extracellular signal-regulated kinase (ERK) pathway in the temporomandibular joint (TMJ) of rats subjected to chronic sleep deprivation (CSD).METHODS: Rats were subjected to CSD using the modified multiple platform method (MMPM).The serum levels of cortic

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The use of gas-dynamic flame stabilization in afterburner combustion chambers of aircraft gas turbine engines

It is LUTEIN impossible to abandon the use of the afterburner combustion chamber in designing advanced gas turbine engines.Well-known and well-established structural designs of afterburners were developed several decades ago and do not meet the requirements imposed upon advanced projects, some of which appeared only now.In this context, it became n

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Comparison of oral anticoagulants for stroke prevention in atrial fibrillation using the UK clinical practice research Datalink Aurum: A reference trial (ARISTOTLE) emulation study.

BackgroundStroke prevention guidance for patients with atrial fibrillation (AF) uses evidence generated from randomised controlled trials (RCTs).However, applicability to patient groups excluded from trials remains unknown.Real-world patient data provide an opportunity to evaluate outcomes in a trial analogous population of direct oral anticoagulan

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Ceftolozane-Tazobactam Treatment of Hypervirulent Multidrug Resistant Pseudomonas aeruginosa Infections in Neutropenic Patients

The effectiveness of ceftolozane/tazobactam for the treatment of infections in neutropenic patients caused by hypervirulent multidrug-resistant (MDR) Pseudomonas aeruginosa has not been previously reported.We identified seven cases of MDR P.aeruginosa infection in neutropenic patients over a four-month period within the same hematology ward.Four ca

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